DAND5 抗体 (AA 23-189)
Quick Overview for DAND5 抗体 (AA 23-189) (ABIN2719202)
抗原
See all DAND5 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 23-189
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产品特性
- Homo sapiens DAN domain family, member 5 (DAND5)
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纯化方法
- Purified from mouse ascites fluids by affinity chromatography
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免疫原
- Human recombinant protein fragment corresponding to amino acids 23-189 of human DAND5(NP_689867) produced in E.coli.
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亚型
- IgG1
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应用备注
- WB 1:500~2000, IHC 1:150, FLOW 1:100,
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说明
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The concentration of the product may vary between diferrent lots.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5-1.0 mg/mL
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缓冲液
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- DAND5 (DAN Domain Family, Member 5 (DAND5))
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别名
- DAND5
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背景
- This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to bind Nodal and to inhibit the Nodal signaling pathway which patterns left/right body asymmetry.
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分子量
- 18 kDa
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基因ID
- 199699
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NCBI登录号
- NM_152654
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HGNC
- 199699
抗原
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